关键字：血栓性微血管病 TMA TTP HUS αHUS 病理学 分子遗传学

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简介：Affects 1-2%/million Most commonly involved organs: Kidney, CNS, GI tract 3 distinct clinical presentations TTP: Typically CNS (stroke-like symptoms) but it can affect primarily the Kidney (AKI) Classic HUS: D+ HUS (STEC-HUS)- Kidney (CNS) Atypical HUS - aHUS